Xiaoyan Wu吴小燕

Postdoctoral Fellow, Psychiatric University Hospital Zurich and Neuroscience Center Zurich (UZH & ETH Zurich)

I study how humans and artificial systems construct models of the world, how these models shape cognition and behavior, and how they differ across systems or become disrupted in psychiatric disorders.

My research combines behavioral experiments, computational modeling, neuroimaging, and analyses of large language models to investigate human cognition and artificial intelligence. I am currently a postdoctoral fellow in the Homan Lab. I received my PhD in Cognitive Neuroscience from the IDG/McGovern Institute for Brain Research at Beijing Normal University, with research experience at the Zurich Center for Neuroeconomics during my PhD.

Portrait of Xiaoyan Wu
University of Zurich Psychiatric University Hospital Zurich ETH Zurich Neuroscience Center Zurich

Research

Humans and AI

How language models judge people's motives

People now ask chatbots why someone acted as they did. I compare large language models with human data and read their internal states with probing and steering. Models turn out to see less malice and more virtue than people do.

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Computational psychiatry

Cognitive maps and disorganized thought

How does the brain build internal maps of knowledge, and what changes in psychosis? I study how relational knowledge is built from images and from language, and how it shows up in natural speech.

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Social decision-making

Human motives for cooperation and altruism

Why do people cooperate, punish and help? I use computational models and neuroimaging to separate the motives behind altruism, trust and cooperation, from childhood to adulthood.

Papers →

News

Earlier news
  • I am looking for Research Assistants to join my team at the University of Zurich. If you are interested in pursuing a PhD in Computational Psychiatry, please contact me. More details.
  • I am recruiting motivated Master's students for a thesis project on language and computational psychiatry at the Homan Lab, University of Zurich and Psychiatric University Hospital Zurich. More details.
  • I was greatly honored to be invited by Prof. Raymond Dolan and presented my recent work, "From Perception to Structure: Cognitive Disorganization Is Linked to Weaker Relational Knowledge Construction", at University College London.
  • I was honored to receive the UZH Postdoc Grant to support my research at the University of Zurich.
  • My study on adolescent cooperation was featured in eLife Press.
  • I attended SIRS 2026 in Florence.
  • I was honored to give an invited talk at Virginia Tech, hosted by Prof. Seongmin Park: "Disorganization impairs cognitive maps built from visual inputs".
  • I attended ABIM 2026 in Champéry and received the Best Poster Presentation Award. Here is my poster.
  • I gave an invited talk at the University of Zurich, hosted by Prof. Todd Hare: "Schizophrenia spectrum disorder and cognitive maps: new findings and future directions".
  • The Christmas markets in Zurich began, and I invited friends and colleagues for a Glühwein after work.
  • I presented my recent work, "Disorganization impairs cognitive maps built from visual inputs", at the 8th Burghölzli Psychiatry Meeting, Zurich.
  • I presented my recent work from the Homan Lab at Universitat Pompeu Fabra (UPF).
  • I was greatly honored to receive the Outstanding PhD Dissertation Award from Beijing Normal University.
  • My research was selected as a Cover Runner-up for Nature Computational Science. View the design.
  • I officially started my postdoc at the University of Zurich.
  • I was honored to give an invited talk at South China Normal University, Guangzhou.
  • I was honored to present at the 22nd Annual Society for Neuroeconomics Meeting in Cascais, Portugal.
  • I successfully defended my PhD dissertation and earned my doctoral degree in Psychology.
  • Prof. Jie Hu wrote a News & Views article on our work on human altruism. A big thanks!
  • Our work on human altruism was accepted in Nature Computational Science.
  • I was honored to give invited talks at Waseda University and the University of Tokyo on human altruism.
  • I was honored to present my work on trust at the Society for Social Neuroscience annual meeting in Tsukuba.
  • I was honored to give an invited talk at Stanford University on neurocomputational components of trust.
  • My visit to Zurich ended, and I returned to Beijing Normal University.
  • I was honored to present at the 21st Annual Society for Neuroeconomics Meeting in Vancouver.
  • I was honored to attend the Neuroeconomics Summer School at the University of Pennsylvania.
  • I completed MRI User Training with a Qualified Certificate at University Hospital Zurich.
  • I was honored to give an invited talk at the University of Zurich on human altruism.
  • I was honored to participate in the Computational Psychiatry Course Zurich 2022.
  • I was honored to give an invited talk at Peking University on inequality aversion and third-party intervention.
  • I started my journey in Zurich as a visiting guest at UZH.

Selected Publications

† Co-first authors. * Co-last authors. Full list on Google Scholar.

AI and language models

Figure 1 of the paper: the whistleblowing scenario and the motive ratings of humans and language models
Large language models underrepresent malice and overreport virtue
Xiaoyan Wu, Fan Shi
arXiv (2026) Preprint

Language models judge a whistleblower's motives more charitably than people do. Reading the model's internal states shows two separate sources: the signal for malevolent motives is weaker inside the model, and benevolent motives are amplified when the model reports its answer.

Study design: disclosure decision, attributed motives and character judgment
Human-like moral judgments conceal divergent motive attributions in large language models
Xiaoyan Wu, Jean-Claude Dreher
arXiv (2026) Preprint

Large language models reproduce human moral evaluations of whistleblowers while attributing systematically different motives to them, so agreement in average judgments can conceal a different attributional structure.

Cognitive maps and psychosis

Paper figure: the two-dimensional conceptual map task and its relation to cognitive disorganization
Disorganization impairs cognitive maps built from visual inputs
Xiaoyan Wu, Finn Rabe, Peizheng Wu, Victoria Edkins, Yves Pauli, Stephanie Theves, Wolfram Hinzen, Iris E. Sommer, Philipp Homan
Schizophrenia Bulletin (2026, in press) DOI

Schizophrenia-spectrum cognitive disorganization selectively disrupts the ability to construct and use internal relational maps from visual input, but not from language, supporting the shallow cognitive map hypothesis.

Speech recording design: self-reflecting versus teaching others
Teaching others reveals hidden structure in conceptual cognitive maps
Xiaoyan Wu, Peizheng Wu, Wolfgang Omlor, Wolfram Hinzen, Iris E. Sommer, Philipp Homan
bioRxiv (2026) DOI

Explaining knowledge to others externalizes spatially structured representations of conceptual memory in naturalistic speech. Cognitive disorganization selectively weakens this effect after image-based, but not language-based, learning.

Social decision-making

Paper figure: the motive cocktail model
The motive cocktail in altruistic behaviors
Xiaoyan Wu†, Xiangjuan Ren†, Chao Liu, Hang Zhang
Nature Computational Science (2024) PaperNews & Views

Third-party punishment and helping are not driven by a single moral impulse. Behavioral experiments and computational modeling identify seven socioeconomic motives, the "motive cocktail", whose mix differs between people and contexts.

Adolescents and adults in a repeated social dilemma
The self-interest of adolescents overrules cooperation in social dilemmas
Xiaoyan Wu†, Hongyu Fu†, Gökhan Aydogan, Chunliang Feng, Shaozheng Qin, Yi Zeng, Chao Liu
eLife (2026) PaperPress release

Adolescents cooperate less than adults not because they understand others less well, but because reciprocity is less rewarding to them, reflecting a stronger self-interest motive.

Computational model of conditional cooperation
A cognitive computational mechanism for mutual cooperation: The roles of positive expectation and social reward
Xiaoyan Wu, Hongyu Fu, Tengfei Zhang, Dongqi Bao, Jie Hu, Ruida Zhu, Chunliang Feng, Ruolei Gu, Chao Liu
Acta Psychologica Sinica (2024) Paper

In the Prisoner's Dilemma, cooperation is best explained by a model that combines the intrinsic reward of reciprocity with learning about what others expect.

Acute stress and third-party intervention
Acute stress during witnessing injustice shifts third-party interventions from punishing the perpetrator to helping the victim
Huagen Wang, Xiaoyan Wu, Jiahua Xu, Ruida Zhu, Sihui Zhang, Zhenhua Xu, Xiaoqin Mai, Shaozheng Qin, Chao Liu
PLOS Biology (2024) PaperPrimer

Acute stress shifts third parties from punishing offenders to helping victims, driven by changes in connectivity between the amygdala and the dorsolateral and ventromedial prefrontal cortex.

Heroic behavior studied in immersive virtual reality
Observing heroic behavior and its influencing factors in immersive virtual environments
Kelou Jin, Jie Wu, Ran Zhang, Shen Zhang, Xiaoyan Wu, Tingting Wu, Ruolei Gu, Chao Liu
Proceedings of the National Academy of Sciences (2024) Paper

Virtual reality makes it possible to study heroism safely. In simulated crime scenes, both the situation and personal attributes such as gender and empathy shape whether people step in.

Social incentives, guilt aversion and psychopathic traits
Social incentives foster cooperation through guilt aversion: An effect that diminishes with primary psychopathic traits
Xiaoyan Wu, Ruida Zhu, Xu Gong, Yuejia Luo, Chao Liu
PsyCh Journal (2023) Paper

Monetary and social incentives both increase cooperation, but people with stronger primary psychopathic traits respond less to social incentives because they discount what others expect of them.

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